植物の環境感覚:刺激受容から細胞応答まで - 文部科学省 科学研究費補助金 新学術領域研究 平成22年度~26年度

細川 陽一郎

2014年度

原著論文

  • Oikawa, K., Matsunaga, S., Mano, S., Kondo, M., Yamada, K., Hayashi, M., Kagawa, T., Kadota, A., Sakamoto, W., Higashi, S., Watanabe, M., Mitsui, T., Shigemasa, A., Iino, T., Hosokawa, Y.*, M. Nishimura* (2015) Physical interaction between peroxisomes and chloroplasts elucidated by in situ laser analysis. Nature Plants, 1: 15035.
  • Yamakawa, T., Maruyama, A., Uedan, H., Iino, T., Y. Hosokawa* (2015) Experimental and calculative estimation of femtosecond laser induced-impulsive force in culture medium solution with motion analysis of polymer micro-beads. Proc. SPIE doi:10.1117/12.2077403.
  • Takenaka, M., Iino, T., Nagatani, A., Y. Hosokawa* (2014) Nanoscale bending movement of biological micro-object induced by femtosecond laser impulse and its detection by AFM. Appl. Phys. Express, 7: 087002_1-4.
  • Iino, T., Lin, PL., Wang, WZ., Deng, JH., Lu, YC., Kao, FJ., Y. Hosokawa* (2014) Contribution of stress wave and cavitation bubble in evaluation of cell-cell adhesion by femtosecond laser-induced impulse. App. Phys. A, 117: 389-93.

受賞

  • 河野達也、細川陽一郎 「氷晶,レーザーで咲く」 第61回応用物理学会春季学術講演会 第3回JAPS PHOTO CONTEST 優秀賞、2015.3.20.
  • Katagiri, D., Sakaguchi, S., Yoneda, A., Demura, T., Y. Hosokawa “Evaluation of trade-off between femtosecond laser manipulation and viability of plant cell” 台湾物理年会 ポスター賞、2015. 1. 28-30.




2013年度

原著論文

  • Hirashima, T.*, Hosokawa, Y., Iino, T., M. Nagayama (2013) On fundamental cellular processes for emergence of collective epithelial movement. Biology Open, doi: 10.1242/bio.20134523.

  • Okano, K.*, Matsui, A., Maezawa, Y., Hee, P.-Y., Matsubara, M., Yamamoto, H., Hosokawa, Y., Tsubokawa, H., Li, Y.-K., Kao, F.-J., H. Masuhara (2013) In situ laser micropatterning of proteins for dynamically arranging living cells. Labo on a Chip, 13: 4078-86.

  • Hagiyama, M., Inoue, T., Furuno, T., Iino, T., Itami, S., Nakanishi, M., Asada, H., Hosokawa, Y., A. Ito* (2013) Increased expression of cell adhesion molecule 1 by mast cells as a cause of enhanced nerve-mast cell interaction in a hapten-induced mouse model of atopic dermatitis. British Journal of Dermatology, 168: 771-778.

総説・解説・著書

  • 細川陽一郎 (2013) フェムト秒レーザー誘起衝撃力により拓く細胞の力場応答ダイナミクス、レーザー研究, 12:.980-984.




2012年度

原著論文

  • Takumi H.*, Kutsuna N., Hosokawa Y., Akita K., Ebine K., Ueda T., Kondo N., and Hasezawa S., (2012) Statistical organelle dissection of Arabidopsis guard cells using image database LIPS, Sci. Rep., Vol. 2, pp.405_1-405-9, doi:10.1038/srep00405.
  • Sakai J., Roldán D., Ueno K., Misawa H., Hosokawa Y., Iino T., Wakitani S., and Takagi M. *, (2012) Effect of the distance between adherent mesenchymal stem cell and the focus of irradiation of femtosecond laser on cell replication capacity, Cytotechnology, Vol. 64, No. 3, pp. 323-329, doi:10.1007/s10616-012-9437-2.

  • Yoshikawa H. *, Hosokawa Y. *, Murai R., Sazaki G., Kitatani T., Adachi H., Inoue T., Matsumura H., Takano K., Murakami S., Nakabayashi S., Mori Y., and Masuhara H. *, (2012) Spatially Precise, Soft Microseeding of Single Protein Crystals by Femtosecond Laser Ablation, Cryst. Growth Des., Vol. 12, No. 9, pp. 4334–4339, doi:10.1021/cg300018t.

  • Ito A. *, Mimae T., Yamamoto Y.-S.-Z., Hagiyama M., Nakanishi J., Ito M., Hosokawa Y., Okada M., Murakami Y., and Kondo T., (2012) Novel application for pseudopodia proteomics using excimer laser ablation and two-dimensional difference gel electrophoresis, Lab Invest., Vol. 92, No. 9, pp. 1374-1385, doi:10.1038/labinvest.2012.98.

  • Iino T. and Hosokawa Y. *, (2012) Controllability of femtosecond laser-induced impulse in water evaluated by local force measurement system using atomic force microscopy , J. Appl. Phys. , Vol.112, No. 6, pp. 066106_1-066106_3, doi:10.1063/1.4754815.

  • Hosokawa Y. *, Ohta M., Ito A., and Takaoka Y., (2012) Photomechanical ablation of biological tissue induced by focused femtosecond laser and its application for acupuncture, Appl. Phys. A, Published online, doi:10.1007/s00339-012-7138-5.

  • Hosokawa C. *, Sakamoto Y., S. Kudoh N., Hosokawa Y., and Taguchi T., (2012) Femtosecond laser-induced stimulation of a single neuron in a neuronal network, Appl. Phys. A, Published online, doi:10.1007/s00339-012-7137-6.

  • Hagiyama M., Inoue T., Furuno T., Iino T., Itami S., Nakanishi M., Asada H., Hosokawa Y., and Ito A. *, (2012) Increased expression of cell adhesion molecule 1 by mast cells as a cause of enhanced nerve-mast cell interaction in a hapten-induced mouse model of atopic dermatitis, Br J Dermatol, Published online, doi:10.1111/bjd.12108.

総説・解説・著書

  • Takaoka Y., Ohta M., Sugano A., Ito A., and Hosokawa Y., (2012) New Technology: Femtosecond laser may be used for future Acupuncture therapy, Acupuncture in Modern Medicine, In press.
  • Hosokawa Y., (2012) Protein crystallization Induced by ultra-short pulse laser (蛋白質の超短パルスレーザー有機結晶化), Cryobio. Cryotech. (in Japanese), Vol. 58, No. 1, pp.15-18.
  • 細川陽一郎, (2012) バイオ分野に注目されるフェムト秒レーザー細胞プロセス, 応用物理, Vol. 82, No. 1, pp.63-67.
  • 熊野 悟, 細川陽一郎, (2012) フェムト秒レーザーによる氷化誘導実験系の作製, 電気学会 光・量子デバイス研究会資料.
  • 細川陽一郎, (2012) 生物に学び、次代を拓く(pp.83-90),ひかりエネルギー革命-グリーンフォトニクス-(NAISTグリーンフォトニクス研究チーム編著), ケイ・ディ・ネオブック.

国際学会(招待講演)

  • Hosokawa Y., (2012) Innovative femtosecond laser applications for investigation of plant perception, The 1st International Symposium on Plant Environmental Sensing, Nara, Japan.
  • Hosokawa Y., (2012) Single Cell Patterning and Modification by Femtosecond Laser Impulsive Force, Energy Material Nanotechnology 2012 EMN Meeting, Orland, USA.
  • Hosokawa Y. and Iino T., (2012) Time Resolved Analysis of Femtosecond Laser Impulse Induced in Water and Cell Culture Medium, 8th International Conference on Photo-Excited Processes and Applications (ICPEPA-8), Rochester, USA.
  • Hosokawa Y., (2012) Femtosecond Laser Manipulation and Analysis of Plant Cells on Frontier of Green Photonics, International Symposium on Green Photonics for Photon-Harvesting Materials and Reactions, Nara, Japan.
  • Hosokawa Y., (2012) Femtosecond Laser Manipulation and Analysis Techniques for Plant on Frontier of Green Technology , GIST-NAIST-NCTU Joint Symposium, Hsinchu, Taiwan.




2011年度

原著論文

  • Man Hagiyama, Tadahide Furuno, Yoichiroh Hosokawa, Takanori Iino, Takeshi Ito, Takao Inoue, Mamoru Nakanishi, Yoshinori Murakami, and Akihiko Ito, (2011) Enhanced nerve-mast cell interaction by a neuronal short isoform of cell adhesion molecule-1, CADM1, J Immunol., Vol. 186, No. 10, pp. 5983-5992

  • Hideaki Yamamoto, Kazunori Okano, Takashi Tanii, Takanori Demura, Yoichiroh Hosokawa, Hiroshi Masuhara, Shun Nakamura, (2011) In-situ guidance of individual neuronal processes by wet femtosecond-laser processing of self-assembled monolayers, Appl. Phys. Lett., Vol. 99, No.16, pp. 163701_1-163701_3

  • Yoichiroh Hosokawa, Haruki Ochi, Takanori Iino, Akihiro Hiraoka, Mikiko Tanaka, (2011) Photoporation of biomolecules into single cells in living vertebrate embryos induced by a femtosecond laser amplifier, PLoS ONE, Vol. 6, No. 11, pp. e27677_1- e27677_7

  • Yoichiroh Hosokawa, (2011) Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for bio-mechanics, Proc. SPIE, Vol. 8204, p. 82041D

  • Okano,K., Yu,D., Matsui,A., Maezawa,Y., Hosokawa,Y., Kira,A., Matsubara,M., Liau,I., Tsubokawa,H. and Masuhara,H. (2011) Induction of the cell-cell connections by using in-situ laser lithography on a perfluoroalkyl-layered cultivation platform. ChemBioChem.

総説・解説・著書

  • 細川陽一郎, 飯野敬矩, 萩山満, 伊藤彰彦, (2012) 原子間力顕微鏡を用いたフェムト秒レーザー誘起衝撃力の定量化-バイオメカニクスへの新しいアプローチ方法-, バイオイメージング, Vol. 20, No. 1, pp. 7-12

  • 細川陽一郎, (2011) ソフトマテリアルのフェムト秒レーザー加工-レーザー誘起衝撃による単一細胞の非破壊加工-, 光アライアンス, Vol. 22, No. 11, pp. 28-30

  • 細川陽一郎, 飯野敬矩, (2011) フェムト秒レーザー誘起衝撃力を利用した細胞接着力の非接触計測(第4章, pp. 33-41), リアルタイム計測による生命現象の解析, シーエムシー出版

  • 細川陽一郎, (2011) バイオ応用(第8章2節10項, pp. 304-306), 先端個体レーザー(レーザー学会編), オーム社

国際学会(招待講演)

  • Yoichiroh Hosokawa, (2011) Non-contact quantification of laser micro-impulse in water by atomic force microscopy and its application for biomechanics, SPIE Smart Nano+Micro Materials and Devices, Melbourne, Australia, Invited.
  • Yoichiroh Hosokawa, (2011) Takahiro Kaji and Hiroshi Masuhara, Three‐dimensional analysis of tightly focused femtosecond laser beam and shockwave propagations in water, ISOT2011 International Symposium on Optomechatronic Technologies, Hong Kong, Invited.




2010年度

原著論文

  • Hosokawa,Y., Hagiyama,M., Iino,T., Murakami,Y. and Ito,A. (2011) Non-contact etimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy. Proc. Nat'l. Acad. Sci , 108 : 1777-1782.

  • Maezawa,Y., Okano,K., Matsubara,M., Masuhara,H. and Hosokawa,Y. (2011) Morphological evaluation of cell differentiation after the isolation of single cells by a femtosecond laser-induced impulsive force. Biomed. Microdevices, 13 : 117-122.

  • Iino,T. and Hosokawa,Y. (2010) Direct measurement of femtosecond laser impulse in water by atomic force microscopy. Appl. Phys. Express, 3 : 107002.

  • Kuo,Y., Wu,C., Hosokawa,Y., Maezawa,Y., Okano,T., Masuhara,H. and Kao,F. (2010) Local stimulation of cultured myocyte cells by femtosecond laser-induced stress wave. Appl. Phys. A, 101 : 597-600.

  • Maezawa,Y., Hosokawa,Y., Okano,K., Matsubara,M. and Masuhara,H. (2010) In situ observation of cell detachment process initiated by femtosecond laser-induced stress wave. Appl. Phys. A, 101 : 127-131.

  • Hosokawa,C., Suzuki,M., Taguchi,T., Kiyohara,A., N.S,Kudoh., Hosokawa.Y., Okano,K. and Masuhara,H. (2010) Micro-channel fabrication by femtosecond laser to arrange neuronal cells on multi-electrode arrays. Appl. Phys. A, 101 : 423-428.

総説・解説・著書

  • 長谷川晴哉、細川 陽一郎、中嶋琢也 (2010)「光ナノ科学への招待」化学同人

新聞・報道

  • 細川陽一郎 読売(朝)18面 2011年3月7日
    「細胞の結合力測る技術開発」
  • 細川陽一郎 朝日新聞(朝)28面 2011年1月18日
    「細胞の「結束力」計測成功」
  • 細川陽一郎 産経新聞(朝)24面 2011年1月18日
    「細胞接着力測定に成功」
  • 細川陽一郎 日経産業新聞(朝)10面 2011年1月18日
    「細胞同士の接着力測定 レーザー衝撃波で」
  • 細川陽一郎 日刊工業新聞(朝)23面 2011年1月18日
    「生きた細胞同士 接着の強さを計測」
  • 細川陽一郎 奈良新聞(朝)11面 2011年1月18日
    「細胞接着する力測定 がん転移解明へ」
  • 細川陽一郎 徳島新聞 2011年1月18日
    「細胞の接着力測定 奈良先端大など技術開発 再生医療・がん解明期待」

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Copyright ©2010 文部科学省科学研究費補助金新学術領域研究「植物の環境感覚:刺激受容から細胞応答まで」